Description

Human islet cells differ from their rodent counterparts. It is important, building on the firm knowledge base provided by studies in cell lines and rodent models, to characterise the human beta cell. The ability to interpret correctly the genetic association and expression data that are now emerging depends critically on accurate information about gene expression in pure fractions of human beta cells. Currently, human islets are obtained from organ donors. Given the major advances in modern endoscopic techniques, it is conceivable that safe and ethical bioptic methodologies for obtaining functional pancreatic tissue could be developed.

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This website is created with material from the European Union FP7-funded DIAMAP project (concluded 2010). The content is continually being reviewed and updated as we are undertaking on-going consultation with the diabetes research community. Progress will be indicated on the road maps. You can send comments on the scientific content through the tab on the right 'make a feedback!'.
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